Book
Genetic studies in an Amish isolate: volume 1
University Microfilms • Ann Arbor, Michigan • Published In 1987 • Pages:
By: Cross, Harold E..
AbstractBrief abstract written by HRAF anthropologists who have done the subject indexing for the document
This document is a genetics study of 9,724 Old Order Amish living in Holmes County, Ohio, in 1964-65. With regard to this study group, the author's specific research objectives are to 1) examine the demographic characteristics (occupational distribution, marriage pattersn, fertility patterns, population growth and composition, incidence of premarital sex, and sterility); 2) ascertain and characterize all cases of hereditary neurologic disorders; 3) determine the frequency of cervical cancer; and 4) estimate the lethal genetic load carried. Cross finds 220 mentally and physically handicapped individuals in 144 families in the study population; he identifies four autosomal recessive neurologic disorders previously unidentified in the genetics literature and finds new evidence on several rare hereditary neurologic disorders, including congenital nystagmus, agoitrous cretinism, and ataxiatelangiectasia. In addition, he identifies and discusses a number of well-known genetic disorders, including mongolism, epidermolysis bullosa, craniosynostosis, cystic fibrosis, hereditary deafness, muscular dystrophy, phenylketonuria, syndactyly and polydactyly, and trisomy 18. Cross finds the incidence of cervical cancer to be lower than among non-Amish women in the same geographical area and attributes this to the differences in the social customs and sexual practices of the two groups. Finally, Cross estimates that the lethal genetic load carried by the Old Order Amish population in Holmes County is comparable to that of non-Amish populations. Volume II of this study contains several appendices that were not included in the analysis. Appendix E, containing the clinical details and case histories of individuals exhibiting the genetic disorders identified by Cross, is included in this document. Test and Schedules Administered in the Field (125) is used to index in this document for information on medical testing of subjects by the author (an M.D.) as part of his research. Where specific reference to the Amish is not given, Theoretical Orientation in Research (121)has been used to index pertinent information on the history of characteristics of given diseases.
- SubjectsDocument-level OCM identifiers given by the anthropology subject indexers at HRAF
- Theoretical orientation in research and its results
- Genetics
- Morbidity
- Life history materials
- Birth statistics
- Tests and schedules administered in the field
- Kinship terminology
- Kin relationships
- cultureCulture name from the Outline of World Cultures (OWC)
- Amish
- HRAF PubDateThe date HRAF published the document
- 2009
- RegionThe area the document pertains to
- North America
- Sub RegionThe more specific area the document pertains to, which is located within the Region
- Regional, Ethnic and Diaspora Cultures
- Document TypeMay include journal articles, essays, collections of essays, monographs, or chapters/parts of monographs
- Book
- Evaluation
- Creator TypeThe type of person writing the document, e.g. Ethnographer, Missionary, Archaeologist, Folklorist, Linguist, Indigenous Person, and so on.
- Physician
- Document Rating A ranking done by HRAF anthropologists based on the strength of the source material on a scale of 1 to 5, as follows: 1 - poor; 2 - fair; 3 - good, useful data, but not uniformly excellent; 4 - excellent secondary data; 5 - excellent primary data.
- 4: Excellent Secondary Data
- 5: Excellent Primary Data
- AnalystThe HRAF anthropologist who subject indexed the document and prepared other materials for the eHRAF culture/tradition collection
- Gerald Reid ; 1988: John Beierle; 2007
- Field DateThe date the researcher conducted the fieldwork or archival research that produced the document
- 1964-1965
- Coverage DateThe date or dates that the information in the document pertains to
- 1800-1965
- Coverage PlaceLocation of the research culture or tradition (often a smaller unit such as a band, community, or archaeological site)
- Holmes County, Ohio, United States
- NotesAdditional notes
- Harold Eugene Cross
- Thesis (Ph.D.)--Johns Hopkins University, 1983
- UM67-14130
- Includes bibliographical references (p. 337-355)
- LCSHLibrary of Congress Subject Headings
- Amish